Paper of the Year

December 2019 : Proof of concept for identifying cystic fibrosis from perspiration samples. Zhou et al. (2019). PNAS 116: 24408-24412.
https://www.pnas.org/content/116/49/24408


December 2019 : A cortical-brainstem circuit predicts and governs compulsive alcohol drinking. Siciliano et al. (2019). Science 366: 1008-1012.
https://science.sciencemag.org/content/366/6468/1008


December 2019 : Correcting a protein network that regulates proteostasis reverses deficits in a mouse model of Down syndrome. Zhu et al. (2019). Science 366: 843-849.
https://science.sciencemag.org/content/366/6467/843


December 2019 : Scalable spider‐silk‐like super tough fibers using a pseudo protein polymer. Gu et al. (2019). Advanced Materials 31: 1904311.
https://onlinelibrary.wiley.com/doi/abs/10.1002/adma.201904311


November 2019 : Data storage in DNA with fewer synthesis cycles using composite DNA letters. Anavy et al. Nature Biotechnology 37:1229–1236.
https://www.nature.com/articles/s41587-019-0240-x


November 2019 : A high-throughput method for amplication-free single-cell whole-genome sequencing can be scaled up to analyze tens of thousands of cells from different tissues and clinical sample types and identifies replication states, aneuploidies, and subclonal m
https://www.cell.com/cell/fulltext/S0092-8674(19)31176-6


November 2019 : Rapid, large-volume, thermally controlled 3D printing using a mobile liquid interface. Walker et al. Science 366: 360-364.
https://science.sciencemag.org/content/366/6463/360


November 2019 : Search-and-replace genome editing without double-strand breaks or donor DNA. Anzalone et al. Nature.
https://www.nature.com/articles/s41586-019-1711-4


November 2019 : Measles virus infection diminishes preexisting antibodies that offer protection from other pathogens. Mina et al. Science 366: 599-606.
https://science.sciencemag.org/content/366/6465/599


October 2019 : A CRISPR-mediated imaging approach, LiveFISH, enables real-time tracking of DNA and RNA in living cells. Wang et al. Science (2019). 365: 1301-1305.
https://science.sciencemag.org/content/365/6459/1301


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