Medical Science

114 Fresh versus Frozen Embryos for Infertility in the Polycystic Ovary Syndrome.

113 The economic burden of physical inactivity.

112 Does physical activity attenuate, or even eliminate, the detrimental association of sitting time with mortality?

111 Body-mass index and all-cause mortality: individual-participant-data meta-analysis of 239 prospective studies in four continents.

110 Phase 3 Trials of Ixekizumab in Moderate-to-Severe Plaque Psoriasis.

109 Indacaterol–Glycopyrronium versus Salmeterol–Fluticasone for COPD.

108 Early rheumatoid arthritis treated with tocilizumab, methotrexate, or their combination.

107 Blue light reduces organ injury from ischemia and reperfusion.

106 Tocilizumab for induction and maintenance of remission in giant cell arteritis.

105 Sustained-release dexamfetamine in the treatment of chronic cocaine-dependent patients on heroin-assisted treatment.

104 In-vivo oesophageal regeneration in a human being by use of a non-biological scaffold and extracellular matrix.

103 Routine pre-procedural rectal indometacin versus selective post-procedural rectal indometacin to prevent pancreatitis in patients undergoing endoscopic retrograde cholangiopancreatography: a multicentre, single-blinded, randomised controlled trial.

102 A Randomized Trial Comparing Skin Antiseptic Agents at Cesarean Delivery.

101 Effects of Testosterone Treatment in Older Men.

100 NETosis and lack of DNase activity are key factors in Echis carinatus venom-induced tissue destruction.

99 Individualizing liver transplant immunosuppression using a phenotypic personalized medicine platform.

98 Mitochondrial iron chelation ameliorates cigarette smoke–induced bronchitis and emphysema in mice.

97 Induction of labour at term with oral misoprostol versus a Foley catheter.

96 A Randomized Trial of Low-Cost Mesh in Groin Hernia Repair.

95 Metformin versus Placebo in Obese Pregnant Women without Diabetes Mellitus.

94 Andexanet Alfa for the Reversal of Factor Xa Inhibitor Activity.

93 Secukinumab, an Interleukin-17A Inhibitor, in Ankylosing Spondylitis.

92 A Trial of Wound Irrigation in the Initial Management of Open Fracture Wounds.

91 Liraglutide safety and efficacy in patients with non-alcoholic steatohepatitis.

90 A new deep proteomic analysis method is used to identify proteins that interact with wild-type cystic fibrosis transmembrane conductance regulator (CFTR) and its mutant version that is the major cause of cystic fibrosis.

89 Tissue transcriptome-driven identification of epidermal growth factor as a chronic kidney disease biomarker.

88 Fourteen babies born after round spermatid injection into human oocytes.

87 Roundworm and hookworm infections are associated with contrasting effects on human reproduction.

86 Early Inhaled Budesonide for the Prevention of Bronchopulmonary Dysplasia.

85 Therapeutic Clearance of Amyloid by Antibodies to Serum Amyloid P Component.

84 Letrozole, Gonadotropin, or Clomiphene for Unexplained Infertility.

83 Phase 3 Studies Comparing Brodalumab with Ustekinumab in Psoriasis.

82 Secukinumab Inhibition of Interleukin-17A in Patients with Psoriatic Arthritis.

81 Daclizumab HYP versus Interferon Beta-1a in Relapsing Multiple Sclerosis.

80 A new therapeutic effect of simvastatin revealed by functional improvement in muscular dystrophy.

79 Direct optical activation of skeletal muscle fibres efficiently controls muscle contraction and attenuates denervation atrophy.

78 Small bites versus large bites for closure of abdominal midline incisions (STITCH): a double-blind, multicentre, randomised controlled trial.

77 Eculizumab in Pregnant Patients with Paroxysmal Nocturnal Hemoglobinuria.

76 A Phase 3 Trial of Sebelipase Alfa in Lysosomal Acid Lipase Deficiency.

75 Initial Use of Ambrisentan plus Tadalafil in Pulmonary Arterial Hypertension.

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