Systems Biology

19 Affinity purification–mass spectrometry elucidates protein interaction networks and co-complexes to build, to our knowledge, the largest experimentally derived human protein interaction network so far, termed BioPlex 2.0.
https://www.nature.com/nature/journal/v545/n7655/full/nature22366.html

18 Long-term neural and physiological phenotyping of a single human.
http://www.nature.com/ncomms/2015/151209/ncomms9885/full/ncomms9885.html

17 A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
http://www.cell.com/cell/abstract/S0092-8674(15)01270-2

16 Systematic analysis of asymmetric partitioning of yeast proteome between mother and daughter cells reveals “aging factors” and mechanism of lifespan asymmetry.
http://www.pnas.org/content/112/38/11977.abstract

15 Automated identification of stratifying signatures in cellular subpopulations.
http://www.pnas.org/content/111/26/E2770.abstract

14 Identifying regulatory mechanisms underlying tumorigenesis using locus expression signature analysis.
http://www.pnas.org/content/111/15/5747.abstract

13 Pulendran and colleagues use a systems biology analysis to reveal distinct transcriptional signatures of antibody responses to different classes of human vaccines.
http://www.nature.com/ni/journal/v15/n2/abs/ni.2789.html

12 Reconstruction of protein networks from an atlas of maize seed proteotypes.
http://www.pnas.org/content/110/49/E4808.abstract

11 Discovery of a kernel for controlling biomolecular regulatory networks.
http://www.nature.com/srep/2013/130717/srep02223/full/srep02223.html

10 Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimers Disease.
http://www.cell.com/abstract/S0092-8674(13)00387-5

9 Pattern discovery and cancer gene identification in integrated cancer genomic data.
http://www.pnas.org/content/110/11/4245.abstract

8 The protein expression landscape of the Arabidopsis root.
http://www.pnas.org/content/109/18/6811.abstract

7 A Systems Biology Approach to Drug Targets in Pseudomonas aeruginosa Biofilm.
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0034337

6 Systems Biology Approaches Reveal a Specific Interferon-Inducible Signature in HTLV-1 Associated Myelopathy.
http://www.plospathogens.org/article/info%3Adoi%2F10.1371%2Fjournal.ppat.1002480

5 A review of imaging techniques for systems biology.
http://www.biomedcentral.com/1752-0509/2/74

4 Initial characterization of the human central proteome.
http://www.biomedcentral.com/1752-0509/5/17

3 Identifying cancer biomarkers by network-constrained support vector machines.
http://www.biomedcentral.com/1752-0509/5/161

2 Network analysis of microRNAs and their regulation in human ovarian cancer.
http://www.biomedcentral.com/1752-0509/5/183

1 Conserved host response to highly pathogenic avian influenza virus infection in human cell culture, mouse and macaque model systems.
http://www.biomedcentral.com/1752-0509/5/190

 
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