Deprecated: mysql_pconnect(): The mysql extension is deprecated and will be removed in the future: use mysqli or PDO instead in /home/dcz25x0vfkvf/public_html/Connections/bscon1.php on line 9
Pharmacology

Pharmacology

Articles:

246 Biosynthesis of medicinal tropane alkaloids in yeast.
https://www.nature.com/articles/s41586-020-2650-9

245 Clinical benefit of remdesivir in rhesus macaques infected with SARS-CoV-2.
https://www.nature.com/articles/s41586-020-2423-5

244 Discovery and engineering of colchicine alkaloid biosynthesis.
https://www.nature.com/articles/s41586-020-2546-8

243 Developing Covalent Protein Drugs via Proximity-Enabled Reactive Therapeutics.
https://www.cell.com/cell/fulltext/S0092-8674(20)30623-1

242 Monomeric insulin stabilized with polymeric excipient exhibits increased stability and faster pharmacokinetics than current rapid-acting insulins.
https://stm.sciencemag.org/content/12/550/eaba6676

241 Galidesivir, a broad-spectrum direct-acting adenosine analog antiviral drug, abrogates viremia in rhesus macaques infected with Zika virus.
https://stm.sciencemag.org/content/12/547/eaau9135

240 Structures of mycobacterial glycosyltransferases define a binding site for an anti-tuberculosis drug.
https://science.sciencemag.org/content/368/6496/1211

239 An amphipathic peptide targeting the gp41 cytoplasmic tail kills HIV-1 virions and infected cells.
https://stm.sciencemag.org/content/12/546/eaaz2254

238 Preclinical validation of a repurposed metal chelator as an early-intervention therapeutic for hemotoxic snakebite.
https://stm.sciencemag.org/content/12/542/eaay8314

237 Elesclomol therapy stops the progression of neurodegeneration and improves survival in a mouse model of Menkes disease.
https://science.sciencemag.org/content/368/6491/620

236 An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice.
https://stm.sciencemag.org/content/12/541/eabb5883

235 An open-source drug discovery platform enables ultra-large virtual screens.
https://www.nature.com/articles/s41586-020-2117-z

234 A dual effect of ursolic acid to the treatment of multiple sclerosis through both immunomodulation and direct remyelination.
https://www.pnas.org/content/117/16/9082

233 A scorpion-derived peptide-steroid conjugate accumulates in cartilage and reverses inflammation in a rat model of arthritis without steroid toxicity.
https://stm.sciencemag.org/content/12/533/eaay1041

232 AB569, a nontoxic chemical tandem that kills major human pathogenic bacteria.
https://www.pnas.org/content/117/9/4921

231 JAK inhibition increases bone mass in steady-state conditions and ameliorates pathological bone loss by stimulating osteoblast function.
https://stm.sciencemag.org/content/12/530/eaay4447

230 Antitumor astins originate from the fungal endophyte Cyanodermella asteris living within the medicinal plant Aster tataricus.
https://www.pnas.org/content/116/52/26909

229 Chimeric peptidomimetic antibiotics against Gram-negative bacteria.
https://www.nature.com/articles/s41586-019-1665-6

228 A new antibiotic selectively kills Gram-negative pathogens.
https://www.nature.com/articles/s41586-019-1791-1

227 A multistep biocatalytic cascade is applied to the synthesis of the experimental HIV drug islatravir.
https://science.sciencemag.org/content/366/6470/1255

Free Images for Presentation: sunipix SUNIPIX