Nutrition & Metabolism


325  Sympathetic neuron–associated macrophages contribute to obesity by importing and metabolizing norepinephrine.

324  Transcription factor ISX mediates the cross talk between diet and immunity.

323  Small-molecule inhibitors directly target CARD9 and mimic its protective variant in inflammatory bowel disease.

322  GFRAL is the receptor for GDF15 and is required for the anti-obesity effects of the ligand.

321  GFRAL is the receptor for GDF15 and the ligand promotes weight loss in mice and nonhuman primates.

320  Inflammasome-driven catecholamine catabolism in macrophages blunts lipolysis during ageing.

319  Caloric restriction delays age-related methylation drift.

318  Inhibition of FABP4 rescues defective apelin signaling, decreases fatty acid accumulation, and promotes insulin sensitivity.

317  The intestinal microbiota regulates body composition through NFIL3 and the circadian clock.

316  Adult-onset obesity is triggered by impaired mitochondrial gene expression.

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