Molecular Biology


516  Double-stranded RNA binding protein, Staufen, is required for the initiation of RNAi in coleopteran insects.

515  MicroRNA-30c-5p modulates neuropathic pain in rodents.

514  Apoptosis propagates through the cytoplasm as trigger waves.

513  A system that targets DNA polymerase activity with CRISPR-guided nickases to provide genetic diversification at user-defined loci enables forward genetic approaches.

512  Three-dimensional intact-tissue sequencing of single-cell transcriptional states.

511  De novo DNA synthesis using polymerase-nucleotide conjugates.

510  Disruption of the beclin 1–BCL2 autophagy regulatory complex promotes longevity in mice.

509  Field-deployable viral diagnostics using CRISPR-Cas13.

508  Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6.

507  CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity.

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