Molecular Biology


527  Chromatin modifiers Mdm2 and RNF2 prevent RNA:DNA hybrids that impair DNA replication.

526  Programmed DNA destruction by miniature CRISPR-Cas14 enzymes.

525  SFXN1 is a mitochondrial serine transporter required for one-carbon metabolism.

524  Mammalian pigmentation is regulated by a distinct cAMP-dependent mechanism that controls melanosome pH.

523  Nuclear cGAS suppresses DNA repair and promotes tumorigenesis.

522  mTOR inhibitors lower an intrinsic barrier to virus infection mediated by IFITM3.

521  An RNA-adapting CRISPR–Cas system is coupled with amplification and sequencing steps to record, retrieve and analyse changes in the transcriptome of a bacterial cell over time.

520  Discovery of widespread type I and type V CRISPR-Cas inhibitors.

519  CRISPR-Cas12a inhibitors that block gene editing in human cells are identified.

518  CRISPR-Mediated Programmable 3D Genome Positioning and Nuclear Organization.

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