Molecular Biology

Articles:

594  TOP1 inhibition therapy protects against SARS-CoV-2-induced lethal inflammation.
https://www.cell.com/cell/fulltext/S0092-8674(21)00382-2

593  QSER1 cooperates with TET1 to safeguard DNA methylation valleys from DNMT3-mediated de novo methylation.
https://science.sciencemag.org/content/372/6538/eabd0875

592  Zinc finger protein E4F1 cooperates with PARP-1 and BRG1 to promote DNA double-strand break repair.
https://www.pnas.org/content/118/11/e2019408118

591  An asymmetric DNA origami shape binds to sites on silica surfaces with a well-defined orientation.
https://science.sciencemag.org/content/371/6531/eabd6179

590  Microbial single-cell RNA sequencing by split-pool barcoding.
https://science.sciencemag.org/content/371/6531/eaba5257

589  Mechanism of membrane-tethered mitochondrial protein synthesis.
https://science.sciencemag.org/content/371/6531/846

588  Human NLRP1 detects long double-stranded RNA during positive-strand RNA virus infection.
https://science.sciencemag.org/content/371/6528/eabd0811

587  Efficient CRISPR-mediated base editing in Agrobacterium spp.
https://www.pnas.org/content/118/2/e2013338118

586  Inactivation of the histone acetyltransferase gene KAT7 prolongs survival in naturally aged mice and progeroid mice that age prematurely.
https://stm.sciencemag.org/content/13/575/eabd2655

585  Metabolic engineering generates a transgene-free safety switch for cell therapy.
https://www.nature.com/articles/s41587-020-0580-6

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