Molecular Biology

Articles:

549  Disease-causing microduplications can be corrected by harnessing an endogenous double-stranded break DNA repair pathway.
https://www.nature.com/articles/s41586-019-1076-8

548  SIRT6 Is Responsible for More Efficient DNA Double-Strand Break Repair in Long-Lived Species.
https://www.cell.com/cell/fulltext/S0092-8674(19)30344-7

547  Insulin Receptor Associates with Promoters Genome-wide and Regulates Gene Expression.
https://www.cell.com/cell/fulltext/S0092-8674(19)30213-2

546  TePhe, a tellurium-containing phenylalanine mimic, allows monitoring of protein synthesis in vivo with mass cytometry.
https://www.pnas.org/content/116/17/8155

545  DISCOVER-Seq enables unbiased identification of off-target sites by CRISPR-Cas nucleases in cellular and in vivo models.
https://science.sciencemag.org/content/364/6437/286

544  Transcriptome-scale super-resolved imaging in tissues by RNA seqFISH+
https://www.nature.com/articles/s41586-019-1049-y

543  Triggering of a Dll4–Notch1 loop impairs wound healing in diabetes.
https://www.pnas.org/content/116/14/6985

542  The Circadian Protein Period2 Suppresses mTORC1 Activity via Recruiting Tsc1 to mTORC1 Complex.
https://www.cell.com/cell-metabolism/fulltext/S1550-4131(18)30683-1

541  Mutations that protect a small guanosine triphosphatase from its normal proteolytic degradation lead to excessive growth factor signaling.
http://science.sciencemag.org/content/363/6432/1226

540  Discovery and Characterization of Cas9 Inhibitors Disseminated across Seven Bacterial Phyla.
https://www.cell.com/cell-host-microbe/fulltext/S1931-3128(19)30040-X

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