Molecular Biology

Articles:

511  De novo DNA synthesis using polymerase-nucleotide conjugates.
https://www.nature.com/articles/Nbt.4173

510  Disruption of the beclin 1–BCL2 autophagy regulatory complex promotes longevity in mice.
https://www.nature.com/articles/s41586-018-0162-7

509  Field-deployable viral diagnostics using CRISPR-Cas13.
http://science.sciencemag.org/content/360/6387/444

508  Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6.
http://science.sciencemag.org/content/360/6387/439

507  CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity.
http://science.sciencemag.org/content/360/6387/436

506  Identification of an ion channel that functions in sour taste sensation in mammals and flies is described.
http://science.sciencemag.org/content/359/6379/1047

505  Cryo-electron microscopy and single-molecule studies reveal that the adaptors BICDR1 and HOOK3 recruit two dynein molecules to dynactin and thereby increase the force and speed of the dynein–dynactin microtubule motor.
https://www.nature.com/articles/nature25462

504  Structure of the yeast oligosaccharyltransferase complex gives insight into eukaryotic N-glycosylation.
http://science.sciencemag.org/content/359/6375/545

503  DNA synthesis from diphosphate substrates by DNA polymerases.
http://www.pnas.org/content/115/5/980

502  Dicer uses distinct modules for recognizing dsRNA termini.
http://science.sciencemag.org/content/359/6373/329

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