Immunology

Articles:

1291  WAVE2 suppresses mTOR activation to maintain T cell homeostasis and prevent autoimmunity.
https://science.sciencemag.org/content/371/6536/eaaz4544

1290  Breaks in mitochondrial DNA cause leakage of mitochondrial RNA into the cytoplasm, enhancing immune surveillance and synergizing with nuclear DNA damage to mount a robust type-I interferon immune response.
https://www.nature.com/articles/s41586-021-03269-w

1289  The inflammasome receptor AIM2 acts independently of the inflammasome to reduce autoimmunity and stabilize regulatory T cells.
https://www.nature.com/articles/s41586-021-03231-w

1288  IL-17 controls central nervous system autoimmunity through the intestinal microbiome.
https://immunology.sciencemag.org/content/6/56/eaaz6563

1287  Platelets release mitochondrial antigens in systemic lupus erythematosus.
https://stm.sciencemag.org/content/13/581/eaav5928

1286  Incorporating TLR9-inhibitory sequences in the AAV vector genome inhibits immunogenicity and enhances transgene expression in multiple animal models.
https://stm.sciencemag.org/content/13/580/eabd3438

1285  Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): preliminary results of a randomised, controlled, open-label, platform trial.
https://www.medrxiv.org/content/10.1101/2021.02.11.21249258v1

1284  Delivery of mRNA vaccine with a lipid-like material potentiates antitumor efficacy through Toll-like receptor 4 signaling.
https://www.pnas.org/content/118/6/e2005191118

1283  Engineered off-the-shelf therapeutic T cells resist host immune rejection.
https://www.nature.com/articles/s41587-020-0601-5

1282  On-demand biomanufacturing of protective conjugate vaccines.
https://advances.sciencemag.org/content/7/6/eabe9444

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