448 Genetic studies of human–chimpanzee divergence using stem cell fusions.
https://www.pnas.org/content/118/51/e2117557118
447 CRISPR-Cas9 effectors facilitate generation of single-sex litters and sex-specific phenotypes.
https://www.nature.com/articles/s41467-021-27227-2
446 Gene therapy for hemophilia.
https://www.nejm.org/doi/full/10.1056/NEJMoa2104205?query=featured_home
445 Microchromosomes are building blocks of bird, reptile, and mammal chromosomes.
https://www.pnas.org/content/118/45/e2112494118
444 Paths and timings of the peopling of Polynesia inferred from genomic networks.
https://www.nature.com/articles/s41586-021-03902-8
443 The genomic history of the Middle East.
https://www.cell.com/cell/fulltext/S0092-8674(21)00839-4
442 The Welwitschia genome reveals a unique biology underpinning extreme longevity in deserts.
https://www.nature.com/articles/s41467-021-24528-4
441 In utero adenine base editing corrects multi-organ pathology in a lethal lysosomal storage disease.
https://www.nature.com/articles/s41467-021-24443-8
440 Prednisolone rescues Duchenne muscular dystrophy phenotypes in human pluripotent stem cell–derived skeletal muscle in vitro.
https://www.pnas.org/content/118/28/e2022960118
439 Mapping enhancer regulation across human cell types and tissues illuminates genome function and provides a resource to connect risk variants for common diseases to their molecular and cellular functions.
https://www.nature.com/articles/s41586-021-03446-x
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