401  A genome-wide polygenic score quantifies inherited susceptibility to obesity, integrating information from 2.1 million common genetic variants to identify adults at risk of severe obesity.

400  Human Gain-of-Function MC4R Variants Show Signaling Bias and Protect against Obesity.

399  Glutaminase Deficiency Caused by Short Tandem Repeat Expansion in GLS.

398  In utero gene editing for monogenic lung disease.

397  Cytosine base editor generates substantial off-target single-nucleotide variants in mouse embryos.

396  Local Determinants of the Mutational Landscape of the Human Genome.

395  Global Genetic Networks and the Genotype-to-Phenotype Relationship.

394  A sleep-inducing gene, nemuri, links sleep and immune function in Drosophila.

393  Introns are mediators of cell response to starvation.

392  A high-resolution human genetic map from whole genomes identifies patterns of recombination and de novo mutation.

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