Cancer Biology

 
952 Cancer-associated fibroblasts suppress SOX2-induced dysplasia in a lung squamous cancer coculture.
https://www.pnas.org/content/115/50/E11671

951 Altered ubiquitination of RAS GTPases is implicated in cancer drug resistance.
http://science.sciencemag.org/content/362/6419/1171

950 Human tumor genomics and zebrafish modeling identify SPRED1 loss as a driver of mucosal melanoma.
http://science.sciencemag.org/content/362/6418/1055

949 Single-cell multiomics sequencing and analyses of human colorectal cancer.
http://science.sciencemag.org/content/362/6418/1060

948 Mannose impairs tumour growth and enhances chemotherapy.
https://www.nature.com/articles/s41586-018-0729-3

947 Cancer-associated mutations are surprisingly common in normal esophageal epithelium from human donors.
http://science.sciencemag.org/content/362/6417/911

946 Human-like hyperplastic prostate with low ZIP1 induced solely by Zn deficiency in rats.
http://www.pnas.org/content/115/47/E11091

945 The metabolite BH4 controls T cell proliferation in autoimmunity and cancer.
https://www.nature.com/articles/s41586-018-0701-2

944 An immunoprecipitation-based protocol is developed to analyse DNA methylation in small quantities of circulating cell-free DNA, and can detect and classify cancers in plasma samples from several tumour types.
https://www.nature.com/articles/s41586-018-0703-0

943 Autophagy maintains tumour growth through circulating arginine.
https://www.nature.com/articles/s41586-018-0697-7

942 Enhanced detection of circulating tumor DNA by fragment size analysis.
http://stm.sciencemag.org/content/10/466/eaat4921

941 Nuclear cGAS suppresses DNA repair and promotes tumorigenesis.
https://www.nature.com/articles/s41586-018-0629-6

940 Stromal Modulation Reverses Primary Resistance to Immune Checkpoint Blockade in Pancreatic Cancer.
https://pubs.acs.org/doi/10.1021/acsnano.8b02481

939 Local Blockade of Interleukin 10 and C-X-C Motif Chemokine Ligand 12 with Nano-Delivery Promotes Antitumor Response in Murine Cancers.
https://pubs.acs.org/doi/10.1021/acsnano.8b00967

938 Enhanced Cancer Vaccination by In Situ Nanomicelle-Generating Dissolving Microneedles.
https://pubs.acs.org/doi/10.1021/acsnano.8b04146

937 Enhanced Transdermal Drug Delivery by Transfersome-Embedded Oligopeptide Hydrogel for Topical Chemotherapy of Melanoma.
https://pubs.acs.org/doi/10.1021/acsnano.8b03800

936 Suppression of stromal-derived Dickkopf-3 (DKK3) inhibits tumor progression and prolongs survival in pancreatic ductal adenocarcinoma.
http://stm.sciencemag.org/content/10/464/eaat3487

935 Chromatin accessibility profiling identifies principles of epigenetic regulation in 23 primary human cancers.
http://science.sciencemag.org/content/362/6413/eaav1898

934 Decreased abundance of TRESK two-pore domain potassium channels in sensory neurons underlies the pain associated with bone metastasis.
http://stke.sciencemag.org/content/11/552/eaao5150

933 Local generation of hydrogen for enhanced photothermal therapy.
https://www.nature.com/articles/s41467-018-06630-2

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