Biotechnology

Articles:

421  Spatial control of in vivo CRISPR–Cas9 genome editing via nanomagnets.
https://www.nature.com/articles/s41551-018-0318-7

420  Engineering the protein secretory pathway of Saccharomyces cerevisiae enables improved protein production.
http://www.pnas.org/content/115/47/E11025

419  An integrative computational approach leverages data from model systems and human genome-wide studies to predict genes that have a functional role in disease.
https://www.nature.com/articles/nbt.4246

418  Harnessing the Noncovalent Interactions of DNA Backbone with 2D Silicate Nanodisks To Fabricate Injectable Therapeutic Hydrogels.
https://pubs.acs.org/doi/10.1021/acsnano.8b02434

417  Enhanced detection of circulating tumor DNA by fragment size analysis.
http://stm.sciencemag.org/content/10/466/eaat4921

416  Asymmetric Membrane for Digital Detection of Single Bacteria in Milliliters of Complex Water Samples.
https://pubs.acs.org/doi/10.1021/acsnano.8b05384

415  Single-molecule DNA-mapping and whole-genome sequencing of individual cells.
http://www.pnas.org/content/115/44/11192

414  On-demand manufacturing of clinical-quality biopharmaceuticals.
https://www.nature.com/articles/nbt.4262

413  Gene editing restores dystrophin expression in a canine model of Duchenne muscular dystrophy.
http://science.sciencemag.org/content/362/6410/86

412  A CRISPR–Cas9 gene drive targeting doublesex causes complete population suppression in caged Anopheles gambiae mosquitoes.
https://www.nature.com/articles/nbt.4245

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