59  A tool for genome-wide design of CRISPR guide RNAs reduces off-target effects and facilitates targeting of the non-coding genome.

58  MicrobeJ, a tool for high throughput bacterial cell detection and quantitative analysis.

57  Fast and sensitive taxonomic classification for metagenomics with Kaiju.

56  An interactive web-based application for Comprehensive Analysis of RNAi-screen Data.

55  Predicting the sequence specificities of DNA- and RNA-binding proteins by deep learning.

54  Orchestrating high-throughput genomic analysis with Bioconductor.

53  Computational design of a leucine-rich repeat protein with a predefined geometry.

52  Hydrogen bond rotations as a uniform structural tool for analyzing protein architecture.

51  Computational design of a self-assembling symmetrical β-propeller protein.

50  Effective diagnosis of genetic disease by computational phenotype analysis of the disease-associated genome.

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