Biochemistry

Articles:

230  Redox and pH gradients drive amino acid synthesis in iron oxyhydroxide mineral systems.
https://www.pnas.org/content/early/2019/02/19/1812098116

229  Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity.
https://www.nature.com/articles/s41586-019-0904-1

228  The CH25H–CYP7B1–RORα axis of cholesterol metabolism regulates osteoarthritis.
https://www.nature.com/articles/s41586-019-0920-1

227  Using a make-on-demand library that contains hundreds-of-millions of molecules, structure-based docking was used to identify compounds that, after synthesis and testing, are shown to interact with AmpC β-lactamase and the D4 dopamine receptor with high affinity.
https://www.nature.com/articles/s41586-019-0917-9

226  Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.
https://www.nature.com/articles/s41467-018-08008-w

225  Two-step pathway for isoprenoid synthesis.
https://www.pnas.org/content/116/2/506

224  Dietary sugar silences a colonization factor in a mammalian gut symbiont.
https://www.pnas.org/content/116/1/233

223  Metabolic reprogramming by the S-nitroso-CoA reductase system protects against kidney injury.
https://www.nature.com/articles/s41586-018-0749-z

222  A metal-binding peptide becomes a potent catalyst for ester hydrolysis.
http://science.sciencemag.org/content/362/6420/1285

221  Mannose impairs tumour growth and enhances chemotherapy.
https://www.nature.com/articles/s41586-018-0729-3

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